Statins and LDL-C in Secondary Prevention—So Much Progress, So Far to Go

So much effort, so little progress?

In colorectal cancer (CRC), the treatment guidelines differ for Union International Contrè Cancer (UICC) stage II and III colon cancer patients. In patients with stage II colon cancer without risk factors such as T4 tumor, tumor perforation, emergency surgical procedure, or less than 12 removed lymph nodes, the low risk of recurrence is justifying no role of adjuvant chemotherapy. It would be c...

Multiple myeloma: so much progress, but so many unsolved questions.

form the results of the first randomized study comparing conventional chemotherapy plus novel agents to tandem high-dose melphalan and ASCT in 402 newly diagnosed MM patients. At the time of the report, with a short follow up, there was no significant difference in OS between the two groups, but PFS was significantly improved in the early HDT arm. Two other ongoing trials, one conducted by the ...

Mental Health Stigma: so much progress and yet a long way to go - Introduction to special issue on stigma.

The dramatic impact of Coronavirus outbreak on air quality: Has it saved as much as it has killed so far?

The outbreak of coronavirus disease (COVID-19) was first reported from Wuhan, China, on December 31st, 2019. As the number of coronavirus infections has exceeded 100,000 with toll deaths of about 5000 worldwide as of early March, 2020, scientists and researchers are racing to investigate the nature of this virus and evaluate the short and long term effects of this disease. Despite it...

Stem Cells So far! Stem Cell Therapy Facts and Principles

Stem cells are cells with the ability to divide for indefinite periods and to give rise to specialized cells.  Stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and conditions.  However, except blood stem cell transfer by bone marrow transplant which has been used as an standard practice for more than 50 years, nearly all of therapeutic potenti...